MTEC Pre-Announcement: Fiscal Year 2026 Multi Topic

The Medical Technology Enterprise Consortium (MTEC) is excited to post this pre-announcement for an upcoming Request for Project Proposals (RPP) soliciting a broad range of medical prototype technological and knowledge solutions related to the Focus Areas of Interest (also called “Focus Area(s)”) listed below. Proposed solutions may include medical techniques, knowledge products, and materiel (e.g., medical devices, drugs, and biologics). Military relevance is a key feature of the upcoming RPP. BACKGROUND: Current wartime operations assume that the United States and our allies will maintain air, land, maritime, space and cyber superiority. Future conflicts against peer and near-peer adversaries are expected to be layered stand-offs and fought across multiple domains. Mission success will be determined by our ability to compete to expand the competitive space, penetrate both strategically and operationally, disintegrate enemy’s defenses, exploit enemy weaknesses, and re-compete to consolidate gains. Medical capabilities play a critical role in each aspect of the future battlespace and must modernize rapidly to maintain Force readiness and increase soldier lethality. FOCUS AREAS: To meet the intent of the RPP, each proposal SHALL specifically address ONLY ONE Focus Area described below. Offerors are not limited to a single proposal submission. Projects that fail to align with only one of these Focus Areas may not be considered for funding. The following general Focus Areas of Interest are not listed in order of importance. The detailed requirements for each area will be described in the upcoming Request for Project Proposals. The anticipated focus areas include, but are not limited to the listing below: •Focus Area 1: Policies and practices for cross-cutting prevention – the aim of this focus area is to develop and evaluate non-training interventions/activities that address risk and protective factors for harmful behaviors. Priority risk/protective factors to address include: morale, fairness, work-life balance, passive leadership, toxic leadership, and workplace hostility. •Focus Area 2: Fostering Service member physical fitness through integrated primary prevention – the aim of this focus area is to develop interventions or trainings to combat the key contributors to obesity and physical inactivity. This focus area encourages offerors to consider resource/environmental constraints and social and psychological barriers present for warfighters when developing solutions. •Focus Area 3: Identify and reduce barriers to help-seeking – the aim of this focus area is to identify and develop solutions against key drivers of help-seeking. Solutions should prioritize high-impact resources/services and Service member populations at elevated risk for harmful behaviors. •Focus Area 4: Prophylactic Solutions to Prevent Battlefield and Complex Traumatic Wound Infections in Austere or Contested Environments – the aim of this focus area is the development of solutions to prevent or delay wound infections (bacterial, fungal, and/or antimicrobial-resistant) following battlefield and complex traumatic wounds, including in austere or contested environments, for use at the point of injury and in prolonged care environments (Roles 1 and 2), without negatively impacting wound healing. High-priority pathogens include Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus, and invasive fungal infections. •Focus Area 5: Pathogen Agnostic Countermeasures for the Treatment of Sepsis Caused by Wound Infection – the aim of this focus area is the development of products, including immune modulators, novel drugs, immunotherapeutics, and other pathogen-agnostic and/or host-directed approaches, to treat sepsis following battlefield and complex traumatic wounds (excluding burn wounds), including in austere or contested environments. •Focus Area 6: Knowledge Product Solutions for the Prevention of Infection in Traumatic Penetrating Wounds – the aim of this focus area is the development of knowledge product solutions to optimize clinical practice guidelines for the prevention of infection in traumatic penetrating wounds. •Focus Area 7: Bacterial Diarrhea Prevention – the aim of this focus area is the development of solutions to prevent bacterial diarrhea resulting from high-priority pathogens (Campylobacter jejuni, enterotoxigenic Escherichia coli, and Shigella) in operational settings. •Focus Area 8: Dengue Fever Prevention and/or Treatment Solutions – the aim of this focus area is the development of prophylactic drugs and vaccines, to prevent all four serotypes of Dengue Fever. •Focus Area 9: Prevention and Treatment of Emerging Infectious Diseases – the aim of this focus area is on developing pathogen-agnostic and/or broad-spectrum solutions for prevention or treatment of Lassa fever virus, Crimean-Congo Hemorrhagic Fever Virus (CCHFV), and various hantaviruses, which are high-consequence pathogens that pose distinct risks to the deployed Joint Force. •Focus Area 10: Musculoskeletal Injury Treatment – the aim of this focus area is the development of solutions for musculoskeletal injury interventions for the pre-hospital environment. Specifically, this focus area seeks (1) therapeutic interventions to accelerate recovery from musculoskeletal injury or (2) solutions for the preservation of musculoskeletal health. •Focus Area 11: Operational Suitability of Existing Pain Treatments – the aim of this focus area is for solutions that inform risk/benefit decisions and create evidence-based recommendations for the Joint Trauma System (JTS) to refine and optimize existing Clinical Practice Guidelines (CPGs) and Tactical Combat Casualty Care (TCCC) protocols. •Focus Area 12: Repurposing and Novel D…