Non-Optical Methods for High Speed Protein Control

DEPT OF DEFENSE

Notice type
Special Notice
Solicitation #
DARPA-SN-26-89
NAICS
541714
PSC
AC12
Posted
June 8, 2026
Response due
December 8, 2026

What this opportunity is

The Department of Defense is seeking innovative solutions for rapidly switchable, non-optogenetic protein domains aimed at real-time cellular control, as part of its DARPA BTO initiative. This opportunity falls under NAICS 541714 and is categorized as a Special Notice, indicating that it is more about market research than a formal solicitation for bids. Small businesses with expertise in synthetic biology and molecular tools may find this opportunity suitable, particularly those looking to engage in post-competitive, awardable projects.

Analysis by Mindy, grounded in the SAM.gov notice.

Description

DARPA BTO will be actively “shopping” the ERIS Marketplace for innovative, post-competitive, awardable solutions that address the need for a new class of rapidly switchable, non-optogenetic protein domains for real-time cellular control. This effort seeks to develop a robust and versatile molecular tool for massless information transfer across a cell membrane, intended to supplement existing synthetic biology platforms.

Source: SAM.gov, as posted. Verify the current solicitation before responding.

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View the original notice on SAM.gov ↗

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